Ribosomes are the sites in a cell in which protein synthesis takes place. Cells have many ribosomes, and the exact number depends on how active a particular cell is in synthesizing proteins.
This process of protein synthesis occurs in two stages - transcription and translation. When a gene is to be expressed, the base sequence of DNA is copied or transcribed into mRNA (messenger RNA).
My laboratory studies the regulatory and structural roles of mRNAs in the cytoplasm. Specifically, we investigate how 3′UTRs regulate protein functions in a manner that is independent of protein ...
Each strand serves two primary purposes: acting as a template during DNA replication and providing instructions for protein synthesis in a process called transcription. Replication and ...
Quality control (QC) is vital to the in vitro transcription (IVT) RNA workflow. Because IVT RNA synthesis generates RNA that scientists use in multiple downstream applications, it is critical to start ...
The process of ribosome biogenesis involves the transcription of rRNA precursors ... which are characterized by defects in ribosome function and protein synthesis. rRNA is one of the most highly ...