Translation of human pluripotent stem cells into cell therapies will require the development of standardized tests for product consistency, stability, tumorigenicity, toxicity and immunogenicity.

Despite advances in therapeutic approaches, lung cancer remains the leading cause of cancer-related deaths. To understand the molecular programs underlying lung cancer initiation and maintenance, we ...

Stem cell transplantation offers promising solutions for tissue regeneration and age-related degeneration, despite challenges ...

as post-fast refeeding leads to a burst in stem-cell-driven regeneration and tumorigenicity,” the researchers conclude. The ...

FC, Calprotectin; FL, Lactoferrin; MPO, Myeloperoxidase; CRP, C-reactive-protein; ESR, Erythrocyte sedimentation rate; ST2, Suppression of tumorigenicity 2, TNFAIP6 ...

Human papillomavirus (HPV) and hyperactivated YAP1 form a YAP1-HPV oncogenic alliance to drive the malignant transformation ...

Metronidazole exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Once metronidazole enters the organism by passive diffusion and activated in the cytoplasm ...

Two year oral studies conducted in rats with erythromycin did not provide evidence of tumorigenicity. Mutagenicity studies have not been conducted. No evidence of impaired fertility that appeared ...

Dr. Laura Stafman joined the faculty of the UAB Department of Surgery as an Assistant Professor in the Division of Pediatric Surgery in October 2023. She graduated from medical school at the ...