神经干细胞在中枢神经系统的生长发育中起着至关重要的作用，但随着神经系统疾病的发生，神经细胞的变性死亡是不可避免的。研究表明，移植的神经干细胞可以替代受损的细胞，还可以通过旁分泌作用促进神经组织再生和恢复正常功能。外泌体作为重要的旁分泌介质，不仅在物质 ...

They discovered that overexpression of ARPC1B in breast cancer cells increased their tumorigenicity and resulted in centrosome amplification, a classic hallmark of Aurora A activity. Indeed ...

In humans, the main molecular energy carrier is adenosine triphosphate (ATP). It is critical for cellular functions all over ...

In this regard, we have recently found that certain cancer cells have lost PTPµ expression. Therefore, we are determining whether restoration of PTPµ expression in cancer cells results in changes in ...

Metronidazole exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Once metronidazole enters the organism by passive diffusion and activated in the cytoplasm ...

Two year oral studies conducted in rats with erythromycin did not provide evidence of tumorigenicity. Mutagenicity studies have not been conducted. No evidence of impaired fertility that appeared ...

Targeting iPSC Tumorigenicity and Preserving Stemness with a Cutting-Edge Liquid Culture System From Cancer Biology to Regenerative Medicine and Beyond: Targeting iPSC Tumorigenicity and Preserving ...

Dr. Laura Stafman joined the faculty of the UAB Department of Surgery as an Assistant Professor in the Division of Pediatric Surgery in October 2023. She graduated from medical school at the ...