Kymera Therapeutics is a biotech company with innovative technology targeting disease-causing proteins, offering promising ...

Dr. Varshavsky's work discovered key aspects of the ubiquitin system, including the first degradation signals (degrons) in short-lived proteins. The ubiquitin system regulates numerous cellular ...

Targeted protein degradation (TPD) is getting a lot of attention as a promising modality to treat a variety of diseases from cancer to Alzheimer’s. By taking proteins down the cell’s own degradation ...

Researchers at the National Institutes of Health (NIH) and their collaborators have identified a protein, known as RNF114, ...

The Nobel Prize in Chemistry was awarded on Wednesday to three scientists who have help unravel some of the enduring secrets ...

Molecule sends 13 of the 17 most common forms of this cancer-related protein to the cell’s garbage-disposal system ...

Mounting evidence showed that the genetic association of ORMDL3 (ORMDL Sphingolipid Biosynthesis Regulator 3) gene polymorphisms with bronchial asthma and various inflammatory disorders. Yet its role ...

Nurix Therapeutics, Inc. (Nasdaq: NRIX), a clinical stage biopharmaceutical company developing targeted protein modulation drugs designed to treat patients with cancer and inflammatory diseases, today ...

The molecular mechanism of high-glucose-induced cognitive impairment in diabetes remains unclear. This work demonstrates that ...

Discover Arvinas Inc.'s groundbreaking patent for bifunctional compounds targeting LRRK2, offering potential treatments for neurodegenerative diseases and inflammation.

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