An expert highlighted unmet needs in treating T-cell acute lymphoblastic leukemia and where research may focus in the future.

A new study provides important insights into how T-cells, a type of immune cell, become activated. Researchers employed a ...

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Engineered receptors could lead to more precisely targeted, effective cancer therapies with fewer side effects than existing ...

引言癌症是当今世界上最具挑战性的健康问题之一，尤其是肺癌，作为致死率最高的癌症类型，每年夺走数百万人的生命。随着研究人员对癌症的深入研究，人们逐渐认识到，癌症不仅仅是恶性细胞的过度增殖，更是一种与“宿主”复杂相互作用的生态系统。肿瘤微环境（Tumor ...

Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor ...

This study presents important findings on the role of CXXC-finger protein 1 in regulatory T cell gene regulation and function. The evidence supporting the authors' claims is solid, with mostly ...