In the presence of a wild-type allele, both the drop-off and reference probes will hybridize with their targets, leading to a double-positive signal. By contrast, in the presence of a mutant ...

and sperm derived from the 129 Sv/J ES cells carrying either the wild-type or mutant protamine allele. The data show convincingly that wild-type and mutant 129 Sv/J sperm are made in equal numbers ...

Blood tests from children hospitalized with malaria found that nearly all were homozygous for the wild type of sickle cell allele. The few sickle cell carriers among them had the mildest cases of ...