G蛋白偶联受体(G protein–coupled receptors GPCRs)指导细胞响应环境信号,包括激素、神经递质和趋化因子。这一过程通过异三聚体G蛋白介导的复杂 ...
The signal transduction cascade begins when adenylyl cyclase, a membrane- bound enzyme, becomes activated by G-protein molecules associated with the adrenergic receptor. Adenylyl cyclase creates ...
Combining classical yeast genetics with molecular biology, we identified genes required for both repression and derepression of ƒbp1 transcription, including almost all of the genes of the cyclic AMP ...
Instead, the "sperm-swim" switch they are targeting is a cellular signalling protein called soluble adenylyl cyclase or sAC. The experimental male pill inhibits or blocks sAC. In the early study ...
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed ...
It has been shown to inhibit the release of adenylyl cyclase and regulate potassium and calcium channels in the central nervous system. These actions can potentially protect the brain and nervous ...