The researchers designed two K-edge metal nanoprobes, made of praseodymium and hafnium. The probes target two proteins in ...

增强软骨细胞外特异性基质Aggrecan和Col II的分泌。针对三维细胞结构中药物渗透能力有限，干细胞分化不均的难题，将TGF-β3负载在MnO 2 纳米管上 ...

Lin Han obtained his BE degree from Tsinghua University in Beijing, P. R. China, and his PhD degree from the Massachusetts Institute of Technology in the area of Bio- and Polymeric Materials. After ...

Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white ...

Erosion results from breakdown of cartilage components, including aggrecan (caused by a disintegrin and metalloproteinase with thrombospondin motifs [ADAMTS] enzymes), the collagen network (caused ...

Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white ...

The quick response is possible as larger proteoglycans associated with tendinopathy (aggrecan and versican) and some glycoproteins (hyaluronan) can be upregulated in a timespan varying from minutes to ...

Medical imaging is no longer in Kansas, Toto, as a team led by Penn State researchers brings traditional black and white ...

It is a connective tissue that covers bone ends in the joints and provides lubrication of the meeting surfaces, allowing the transmission of loads with a low frictional coefficient. Aggrecan, collagen ...

So, what does that mean? Well, collagenase is an enzyme that degrades protein molecules, including collagen and aggrecan. Therefore, anti-collagenase can help prevent the degradation of these proteins ...