The allele frequency represents the incidence of a gene variant in a population. Alleles are variant forms of a gene that are located at the same position, or genetic locus, on a chromosome.

The association between the HLA-DRB1*01:03 allele and ulcerative colitis has been noted previously, but there is a clinical need for biomarkers that could identify which patients are more likely ...

Researchers found that a chromosome 6 locus within the HLA region was significantly associated with severe vs less severe ulcerative colitis.

The HLA-DRB1*01:03 allele explained this association overall (OR 3.32, 95% CI 2.25-4.89, P=1.45 × 10-9) and in the two ...

An ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to infectious diseases like influenza, according to a new study.

"I think in medicine, just like in society, we see death as a failure -- and we do everything we can to avoid failure." -- ...

The study identifies links between gut microbiota, genetic variants in IBD, and mental health disorders, offering insights ...

A fatal, highly hereditary illness with no disease-modifying treatments, Huntington’s is long overdue for a therapeutic win.

Researchers have discovered that a gene variant, KIR3DL1*114, linked to Denisovans, may impact the immune response in First ...

With Eisai and Biogen’s Leqembi and Eli Lilly’s Kisunla launching onto the market, the 2024 Clinical Trials of Alzheimer’s ...

Good morning, and welcome to the Wave Life Sciences Third Quarter 2024 Financial Results Conference Call. At this time, all participants are in a listen only mode. As a reminder, this call is being ...