We review electron microscope safety, negative staining, carbon coating and cryo-EM grid-freezing protocols in a one-on-one format. Users can schedule troubleshooting consultations with core staff as ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

Researchers used advanced electron microscopy to capture 3D images of RNA nanoparticles during folding, revealing new ...

The University of Colorado Boulder Biochemistry Department's Krios Electron Microscopy facility (BioKEM) offers single particle cryo-EM and cryo tomography of plunge-frozen samples. The BioKEM ...