"The effort of producing high-resolution cryo-EM images is wasted if they are compromised by poor sample preparation," Usukura says. He advises that a good sample for cryo-EM is, most importantly ...

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

What is Cryo-Electron Microscopy? Cryo-electron microscopy (cryo-EM) is a powerful technique used to determine the three-dimensional structure of biological macromolecules, such as proteins and ...

For the first time, researchers at the University of California San Diego report near-atomic-resolution images and video of nitrogenase during catalysis using cryogenic electron microscopy (cryoEM).

Researchers performing cryo-EM experiments can acquire the training to make their own cryo-EM and negative-stain grids, and collect and process their own high-resolution data. We also offer sample ...

“Cryo-EM allows us to peer into a world that we simply ... Subsequently, a 3D map of the target protein is created using ...

This was because the resulting images were little more than blobs - hence the rude description of "blobology" by its detractors. But over time, scientists refined cryo-EM to the point that it ...

This “exposure” yields many 2-D images of the molecules at different angles, which algorithms then merge into one 3-D model. At first cryo-EM rendered molecules as vague lumps, so some ...

Using high-resolution cryo-electron microscopy researchers uncovered unprecedented detail of gyrase’s action on DNA.

In a groundbreaking development, researchers from the United States and Denmark have successfully captured 3D images of ...