This “exposure” yields many 2-D images of the molecules at different angles, which algorithms then merge into one 3-D model. At first cryo-EM rendered molecules as vague lumps, so some ...

Purdue Uni Cryo-EM was used to determine the structure of ... Over a few months, 3-D images of the virus at atomic resolution were generated and researchers could start searching for potential ...

This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...