For other drugs, such as dihydrofolate reductase inhibitors, overexpression of their target predicts resistance. Other potential drug targets are overexpressed in many types of cancer, but this ...

TAXIS Pharmaceuticals highlights strategies for targeting the core mechanisms of resistance and shares a vision of a more ...

Methotrexate sodium tablets are a dihydrofolate reductase inhibitor indicated for the: Treatment of adults with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance ...

Northvale, New Jersey-- (Newsfile Corp. - August 27, 2024) - Elite Pharmaceuticals, Inc. (OTCQB: ELTP) ("Elite" or the "Company"), a specialty pharmaceutical company developing niche generic products, ...

India: A recent case report published in Cureus underscores the serious risks associated with methotrexate toxicity, ...

Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the required enzyme, dihydrofolate reductase. Dilute (see full labeling ...

Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the required enzyme, dihydrofolate reductase. 1 DS tab, 2 regular tabs ...

Methotrexate sodium tablets are a dihydrofolate reductase inhibitor indicated for the: Treatment of adults with acute lymphoblastic leukemia (ALL) as part of a combination chemotherapy maintenance ...