Studies in knockout mice and cultured chondrocytes indicate an important role of corin and atrial natriuretic peptide-mediated signaling in endochondral ossification and bone development.

Skeletal stem cells have been isolated from various tissues, including periosteum and bone marrow, where they exhibit key functions in bone biology and hematopoiesis, respectively. The role of ...

Gene set enrichment analysis revealed robust expression of markers enriched in osteoblast proliferation and maturation and endochondral ossification pathways in Clec14a-/-samples. Further ...