克氏综合征是男性不育的常见遗传学病因之一 患者表现为较正常男性多一条X染色体随着辅助生殖技术的发展部分克氏综合征患者可以通过睾丸显微取精术获得后代但仍有近一半的患者无法获得可用精子 几十年来，研究多集中在成人阶段此时生殖细胞已大量丢失 北京大学乔杰/ ...

基于前期研究中发现的人类FGC在早期发育过程中存在X染色体重新激活这一关键特征，团队提出，克氏综合征患者胎儿期的生殖细胞可能已经出现X染色体剂量异常，并可能是其生殖障碍的分子基础。因此，研究胎儿期的生殖细胞可能是发现发育异常的关键，团队对此开展了深入 ...

How does an extra X chromosome lead to infertility in men? Professor Qiao Jie and her team at Peking University Third ...

Researchers found that neural crest stem cells are uniquely capable of reprogramming, challenging current reprogramming ...

A chemical in common-use plastics may cause DNA damage and infertility in women, a new Harvard Medical School study shows.

A team led by researchers at the University of Toronto has discovered that a group of cells located in the skin and other ...

Direct reprogramming of one cell type to another may not be probabilistic, but deterministic, suggests a study focused on ...

Neural crest stem cells, a rare type found in skin and other tissues, are uniquely capable of reprogramming into different ...

Nonobstructive azoospermia (NOA) affects 5%–15% of men undergoing infertility evaluation, accounting for nearly 60% of ...