Histologic examination of lungs obtained from hyperoxic pups revealed a remarkable arrest of alveolarization compared with their normoxic littermate controls. Hyperoxia-exposed lungs demonstrated ...

A wish to alleviate tissue hypoxia underlies the common clinical use of hyperoxic ventilation in shock. Yet, this straightforward approach is met by skepticism that is based on the potential pro ...

Background and aims: We have recently shown that Dextromethorphan is neuroprotective against excitotoxic and hyperoxic-induced brain injury. Beside its antagonistic effect on the NMDA [N-methyl-D ...

The retina becomes relatively hyperoxic which will cause vasoconstriction, vaso-obliteration and will inhibit new blood vessel formation by down-regulating VEGF expression. [55] This may cause a ...

Take Interval Hypoxic-Hyperoxic Training (IHHT), for instance. Similar to altitude training, IHHT consists of a 45-minute treatment wearing a specialised breathing mask. Throughout the duration of ...

BMC Genomics, 4;20(1):105. * co-first authors. *Undergraduate researcher Yuhao Zhang, Cristian Coarfa, Xiaoyu Dong, Weiwu Jiang, Brielle Hayward-Piatkovskyi, Jason Gleghorn, and Krithika Lingappan ...