近期，科学家Victor Ambros和Gary Ruvkun获得2024年“诺贝尔生理学或医学奖”，表彰其发现MicroRNA（miRNA）及其转录后的基因调控作用。毋庸置疑，miRNA的发现开创RNA调控基因的新纪元。

The biogenesis of miRNAs involves a multi-step process that begins in the nucleus and ... The pre-miRNAs are exported to the cytoplasm, where they are further cleaved by the Dicer enzyme to generate ...

Pri-miRNA is illustrated with ribbons. Microprocessor is a trimeric complex, consisting of DROSHA (green) and DGCR8 dimer (yellow). The background is the word cloud generated using our lab's ...