This shift in focus brings attention to prodrugs – medications that start as inactive or less active, and once inside the ...

Join us for the final broadcast of this year's symposium as John Higgins explains how prodrugs can be pursued early in discovery space in order to optimize drugs’ physicochemical and biopharmaceutical ...

Experiments in which they tested the effectiveness of activating the prodrugs in cell culture on colon and prostrate cancer cells showed the antibody to be effective at therapeutically relevant ...

Researchers from IOCB Prague have succeeded in preparing compounds capable of activating prodrugs at predetermined locations in the body, enhancing their effectiveness and expediting their action.

Prodrugs are medications that start as inactive or less active, and once inside the body, are converted into the active form, ...

Medivir is developing tumor-directed nucleotide oral prodrugs to treat cancers with highly unmet medical needs. The company’s lead drug candidate, MIV-818, is a liver cancer targeted prodrug ...

MAIA will present the results of preclinical studies for its new THIO-based prodrugs, designated as MAIA-2021-20 and MAIA-2022-12, which are lipid-conjugated compounds derived from THIO.

The Danish pharma group is pledging $285 million in upfront and milestone payments for the lead GLP-1 asset in the ...

The drug will be marketed under the trade name Vyalev. Vyalev is a solution of carbidopa (CD) and levodopa (LD) prodrugs, which are the standard of care for PD patients. Prodrugs are medications ...

Vyalev, previously known as ABBV-951, features foscarbidopa and foslevodopa, which are the prodrugs for standard-of-care medicines carbidopa and levodopa. Prodrugs are drug derivatives that become ...

TORONTO, ON / ACCESSWIRE / October 15, 2024 / Ripple Therapeutics Corporation, a clinical stage company focused on improving ...