This useful study examines the function of the rnc gene, which encodes the RNase III ribonuclease, as it relates to virulence of Salmonella Enteritidis. The authors demonstrate that the rnc gene is ...

In an approach that took its cue from a classic experiment with crystals of ribonuclease A, vanadate was used as a transition state analog in the catalytic center of the hairpin ribozyme 12.

The authors initially noted an unexpected difference in the ability of tight-binding ligands to impair the degradation of the enzyme dihydrofolate reductase (DHFR) or of the ribonuclease barnase ...

The aqueous solution of nucleic acid can be removed with a pipette. The effective way to remove RNA is with the enzyme ribonuclease, which will rapidly degrade these molecules into ribonucleotide ...

This valuable study reveals extensive binding of eukaryotic translation initiation factor 3 (eIF3) to the 3' untranslated regions (UTRs) of efficiently translated mRNAs in human pluripotent stem ...

HCM is a relatively common genetic cardiomyopathy that can be a challenge to diagnose, with about one in three patients misdiagnosed as having another cardiomyopathy. Genetic testing identifies a ...

In 2005, Henkels was awarded a PhD from the Duke University Department of Biochemistry for his work on the biophysical characterization of ribonuclease P protein, an intrinsically disordered protein.