了解天然稳定酶的热稳定机制，提高不稳定酶的热稳定性是酶工程研究的重要内容。尽管现有的蛋白质设计工具和深度学习技术取得了一定的进展，然而准确预测突变对蛋白质热稳定性的影响仍然充满挑战。近日，中国农业科学院姚斌院士团队涂涛组和杭州力文所王浩博博士团队合作 ...

But to realize these potential benefits, researchers first need to overcome challenges and decrease toxicity, increase their ability to escape from the endosomes, increase their thermostability ...

Protein engineering involves three steps: choosing the protein changes (engineering strategies, such as rational design or randomization), making those changes (mutagenesis) and evaluating the ...

Major contributions of the Picotti group include the development of structural proteomics technologies to probe in situ protein structural changes, the characterization of the determinants of proteome ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Dr. Sven K. Weber: As a pioneer in phytase for more than 35 years, we at BASF build on our strengths and distinct know-how as ...