Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...

Researchers generate cutting-edge mouse models by engrafting human cells and tissue into the animals to better study the human immune system. Scientists have employed mouse models in immunological ...

Variants of the PER3 gene disrupt adrenal adaptation to winter light, leading to serotonin disruption and depression-like ...

Another set of germ-free mice were colonized with microbiota from human infants—either from those who had been treated with ...

Kobe University immuno-oncologist SAITO Yasuyuki and his team developed a mouse model with a humanized immune system. With this they successfully tested a new therapeutic approach in which immune ...

If you want to look at human tumours, you need mice with a functional human immune system. So that’s really where humanized mice came into play. Steve Festin: In many ways, it was actually ...

More than 20 years after the first successful engraftment of human leukocytes and hematopoietic organs in mice, scientists met for the 2nd International Workshop on Humanized Mice to discuss ...

SEATTLE-- ( BUSINESS WIRE )--Taconic Biosciences, a leader in genetically engineered rodent models and services, announces ...