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This review provides an overview of the use of antihistamines in children. We discuss types of histamine receptors and their mechanism of action, absorption, onset and duration of action of ...

Pleural infection (parapneumonic effusion and empyema) has an annual incidence of 3.3 per 100 000 children. The incidence of childhood empyema may be increasing in the UK. If so, it is not clear ...

Correspondence to Dr Protima Amon, Centre for Immunobiology, Blizard Institute, 4 Newark Street, London E1 2AT, UK; p.amon{at}qmul.ac.uk There has been an explosion in our understanding of the human ...

Next generation sequencing (NGS), massively parallel or deep sequencing are related terms that describe a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human ...

Correspondence to Professor Alan Cribb, Centre for Public Policy Research, King's College London, London, UK; alan.cribb{at}kcl.ac.uk Quality improvement (QI) has tremendous potential to tackle the ...

1 Department of Paediatric Respiratory Medicine, Southampton Children's Hospital, Southampton, UK 2 Department of Paediatric Intensive Care, Southampton Children's Hospital, Southampton, UK 3 National ...

Correspondence to Dr Elaine S Ramsay, Department of Rheumatology, The Children's Hospital of Philadelphia, 34th and Civic Center Blvd, Philadelphia, PA 19104, USA; RamsayE{at}email.chop.edu The ...

This paper explores the challenges of resolving conflicting feelings around talking with a child about their terminal prognosis. When children are left out of such conversations it is usually done ...

Salbutamol has become a key drug in respiratory medicine since it was first developed by Sir David Jack et al in 1968, 5000 years after the β agonist ephedrine was first used in its raw form, as the ...

Correspondence to Dr Jan Dudley, Department of Paediatric Nephrology, Bristol Royal Hospital for Children, Bristol BS28BJ, UK; jan.dudley{at}uhbristol.nhs.uk The use of data to challenge and improve ...