外胚层干细胞 (EpiSC) 是源自体外植入后晚期外胚层的多能细胞。 EpiSC 无法促成嵌合，表明与内细胞团阶段鼠胚胎干细胞 (mESC) 相比，EpiSC 的多能性较差，代表较晚的发育多能状态。 使用化学方法，我们发现用小分子抑制剂阻断 TGFbeta 途径或抑制组蛋白去甲基酶 ...

ICOC Governing Board/Application Review Subcommittee June 27, 2024 Transcripts Minutes ...

What is the California Institute for Regenerative Medicine (CIRM)? CIRM, California’s Stem Cell Agency, was created by the voters of California in 2004 when they overwhelmingly passed Proposition 71, ...

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and ...

There is no shortage of myths and misconceptions when it comes to stem cell research and regenerative medicine. Here we address the most common concerns. If you have more questions that aren’t ...

have the ability to divide and create an identical copy of themselves, a process called self-renewal; and can also divide to form cells that mature into cells that make up every type of tissue and ...

The statewide network is designed to overcome manufacturing bottlenecks that have delayed or stalled development and approval of regenerative medicines. “These awards are a critical first step in ...

The Induced Pluripotent Stem Cell (iPSC) Repository is a major effort from CIRM to create a collection of stem cells developed from thousands of individuals. CIRM is creating the iPSC bank so that ...

Our Agency funds clinical trials testing promising stem cell or gene therapies for currently incurable diseases or disorders to help patients with unmet medical needs. For basic information about stem ...

The CIRM-funded Alpha Clinics form a network of leading medical centers across California, specializing in delivering stem and gene cell clinical trials. The Network’s success is driven by its ability ...

The Alpha Clinics Network is pursuing its goal to accelerate the development and delivery of stem cell treatments to patients through high quality clinical trials. Browse the list of ongoing trials at ...

ReMIND-L (DISC4) applications now closed. ReMIND-X applications expected to post in Q4 2024. The mission of the California Institute for Regenerative Medicine (CIRM) is to accelerate world-class ...