It has now been 25 years since prourokinase was in the spotlight as a potential treatment for acute ischaemic stroke. In 1999, the PROACT-II randomised controlled trial compared intra-arterial ...

In the early 1990s, a pivotal randomised trial sponsored by the National Institute of Neurological Disorders and Stroke ...

The following is a summary of “Tenecteplase versus alteplase for acute stroke within 4·5 h of onset (ATTEST-2): a randomised, parallel group, open-label trial,” published in the November 2024 issue of ...

The Clinical Consultation section features articles that provide brief advice on how to handle specific drug therapy problems. All articles are based on a systematic review of the literature.

The right therapy to address childhood trauma can help create a positive outlook. It’s beneficial whether you start as a child or an adult. Types include narrative exposure, prolonged exposure ...

These resistant thrombi include both arterial and venous types, particularly those linked to ischemic stroke and deep vein thrombosis. Clot recalcitrance to tPA therapy is largely due to neutrophil ...

and hematuria in a patient with coagulopathy who had documented hematuria before alteplase therapy. Bleeding did not occur in any patients receiving concurrent antico-agulants or thrombolytics or ...

Heat therapy, also known as thermotherapy, is a common treatment modality for easing pain, reducing muscle stiffness, and promoting circulation to enhance the healing process. It involves the ...