This valuable study reports the first characterization of the CG14545 gene in Drosophila melanogaster, which the authors name "Sakura." Acting during germline stem cell fate and differentiation, ...

Keywords: antibodies repertoire, immune system, B-cell repertoire, B-cells, The antigen receptor repertoires of B-cells, antigen receptor repertoire, antibodies, immunoglobulin germline genes ...

Design of clinical trials for germline gene editing stretches current accepted standards for human subjects research. Among the challenges involved is a set of issues concerning intergenerational ...

The lambda chain seems to be encoded by two separate germ-line genes (a specificity region gene and a common region gene) which are expressed as a single, continuous polypeptide chain. Antibody ...

Ovary representing sheath cells, terminal filaments, cap cells, germline stem cells, germline cells with intermingled cells and swarm ... In L, triangles indicate numbers less than 1 were raised to 1.

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical ...

1ADC Therapeutic Development, Zymeworks Inc., Vancouver, Canada.

耶鲁大学医学院Akiko Iwasaki团队在Science Immunology上发表题为"A B cell screen against endogenous retroviruses identifies glycan-reactive IgM that recognizes a broad array of enveloped viruses的研究论文。

Objective Immune complexes (ICs) play a critical role in the pathology of autoimmune diseases. The aim of this study was to generate and characterise a first-in-class anti-FcγRIIA antibody (Ab) ...