In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

Psoriasis is a multifactorial immune-mediated inflammatory disease. Its pathogenesis involves abnormal accumulation of neutrophils and T-cell related abnormalities. Pyroptosis is a type of regulated ...

13 However, the phenotypes of these cells are yet to be fully characterised. Apoptosis pathways have also been described as an important signalling cascade implicated in the biology of Achilles ...

The Krebs cycle byproduct itaconate regulates immune cell function, however its role within tumor cells remains unclear. Here ...

NOD2-mediated physiological inflammation is critical for maintaining intestinal homeostasis. The deubiquitinating enzyme YOD1 ...

Survivin: IAPs suppress host cell death in response to viral infection. By binding to caspases, they directly inhibit apoptosis. Survivin and xIAP are members of this family, differing perhaps in ...