Apoptosis is a mechanism of programmed cell death and is essential for development and homeostasis. Cell stress stimulates pro-apoptotic signalling pathways that activate caspase proteases and ...

The Krebs cycle byproduct itaconate regulates immune cell function, however its role within tumor cells remains unclear. Here ...

Psoriasis is a multifactorial immune-mediated inflammatory disease. Its pathogenesis involves abnormal accumulation of neutrophils and T-cell related abnormalities. Pyroptosis is a type of regulated ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Z-DNA-binding protein 1 (ZBP1) is an ...

Flow cytometric data were acquired using a FACSCalibur flow cytometer (Becton Dickinson, San Jose, CA, USA) and analyzed using FlowJo software (version 8.7; Tree Star, Ashland, OR, USA). Cells were ...

Analysis was performed using SpectroFlo (Cytek Biosciences) for raw data unmixing and downstream analysis was performed using Flowjo v10.10 (BD Biosciences). ARPE-19 were seeded on glass coverslips, ...

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