New research shows astrocytes can remove Alzheimer’s-related amyloid-beta via autophagy, offering a promising new direction ...

A research team has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel ...

A study reveals caffeine's potential to enhance heart health by improving endothelial function in systemic lupus ...

An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy ...

Aging is an inevitable phenomenon and is accompanied by several comorbidities. To this end, research into the effects of ...

An analysis of 1,000 genetically diverse mice on different types of calorie-restricted diets and intermittent fasting shows ...

Autophagy is a process by which cellular material is degraded by lysosomes or vacuoles and recycled. Several autophagy pathways operate within a cell, including macroautophagy, microautophagy and ...

In mammals, autophagosome formation, a central event in autophagy, is initiated by the ULK complex comprising ULK1/2, FIP200, ATG13, and ATG101. However, the structural basis and mechanism of the ULK ...

Autophagy is a natural process by which a cell breaks down old, damaged, unnecessary, or dysfunctional components within a cell and then repurposes those components for fuel and to build or maintain ...

Melanoma-associated antigen A6 (MAGEA6) is well known to have oncogenic activity, but the underlying mechanisms by which it regulates tumor progression and chemo-resistance, especially in ...

Autophagy, a vital cellular process responsible for maintaining homeostasis by degrading and recycling cellular components, has emerged as a critical area of research in recent years (Nakashima et al.

Josephine Thinwa shares her journey to becoming a physician scientist and how this led her to investigate the role of a ...