How did you discover MCBAs? Bile acids were first described chemically in 1849, and Heinrich Wieland was awarded a Nobel Prize in 1927 for comprehensively describing their chemistry. This ...

Higher blood levels of bile acids, molecules that aid fat absorption in the gut, are linked to slower MS progression, per ...

Peking University-led researchers have modified an existing treatment for liver disease that does not cause itchiness, a ...

Addressing the challenge of cholestatic itch, the scientific community has been pursuing innovative solutions. Recently, researchers from Peking University, led by Professor Lei Xiaoguang, in ...

Intercept’s US president Vivek Devaraj said the pharma company still believes in the evidence supporting the liver disease ...

Geoffrey Toi's eight-year-old son, Christopher, is the only person in Singapore with a medical condition known as Bile Acid ...

Bile is a green, yellow, or brownish liquid that your liver produces and stores in the gallbladder. Your bile is made up of mainly water but also includes bile salts, amino acids, cholesterol, ...

The FDA informed Intercept that it is unable to approve the sNDA in its current form, consistent with the outcome of the Gastrointestinal Drugs Advisory Committee (GIDAC) meeting in September 2024. In ...

Gill Rich was 50 when she was diagnosed with a rare, chronic liver disease that left her severely fatigued When Gill Rich ...

A man who was turned down for disability benefits twice, despite having a chronic stomach condition, has told family members ...

RTY-694 targets two ABC transporters, ABCB4 and BSEP. BSEP shuttles bile acids from liver cells into bile, while ABCB4 transports the phospholipid phosphatidylcholine, which is critical for ...

It shows that a pressure-sensing protein called PIEZO1 detects blood flow rate through the vein, sparking a chemical chain reaction which turns cholesterol in the blood into bile acids to be ...