HSCs undergo a complex journey first migrating to the fetal liver (FL) and from there to the fetal bone marrow (FBM), where they mostly remain during adult life. In this process, a pool of adult HSCs ...

Bone marrow is a spongy organ that fills the center of various bones of your body. It is where stem cells produce red and white blood cells and platelets. Without bone marrow, you couldn't move oxygen ...

Bone marrow is a soft, spongy material inside your bones where blood cells are made. These blood cells are important for a healthy immune system. (Photo Credit: Wendy Hiller Gee/Eric Olson/WebMD ...

After bone marrow transplantation ... occurs through cell fusion of hepatocytes with HSC progeny cells, most likely macrophages. Shown are the differentiation of hematopoietic cells to myeloid ...

Since cases of radiation disaster may occur, and since bone-marrow deficiency from radiation or chemotherapy does occur in the normal course of clinical medicine, an effort has been made to ...

Specifically, dHSCs constitute a unique reserve pool of HSCs, mobilized only under stress conditions to protect the HSC compartment throughout life ... Following their emergence, HSCs migrate to the ...

2 months earlier, she had presented with pneumonia and was found to have anaemia, thrombocytopenia, and circulating B-lymphoblasts in her peripheral blood. Bone marrow biopsy confirmed a diagnosis of ...

Aplastic anemia occurs when your bone marrow doesn’t make enough red and white blood cells, and platelets. Having fewer red blood cells causes hemoglobin to drop. Hemoglobin is the part of blood that ...

Engraftment in stem cell transplantation is when your body accepts the transplanted bone marrow or stem cells, and they begin to produce new blood cells and immune system cells. It is a step in a ...

From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...