Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

Traditional Chinese medicine (TCM), with its multi-component, multi-pathway and multi-target characteristics, offers unique advantages and broad prospects in the treatment of GLM. Here, we review the ...

This review article comprehensively investigates the mechanisms underlying the beneficial effects of boron compounds in wound healing. Boron exerts its healing properties through multiple pathways, ...

Lesional scalp biopsies were collected at baseline, week 24, and week 48. The co-primary endpoints were changes in lesional expression of CCL5 and fibrosis-related markers, as well as safety at week ...

The alternative complement pathway plays a key role in the pathogenesis of IgA nephropathy. Iptacopan specifically binds to factor B and inhibits the alternative pathway. In this phase 3 ...

Agencies have a new way to connect with qualified early-career workers and move them from the Pathways Program into full-time federal jobs. Two new “talent programs” on USAJobs, which the Office of ...

The Pathways to Prevention project was a collaboration between Griffith University, Education Queensland and Mission Australia which operated from 2002 until 2011, with the project team finding an ...

Department of Gynecological Oncology, Hunan Cancer Hospital/the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, P.R. China. *Corresponding Author: ...

To link the Rap1A impact on SOCE to CRAC channels encoded by Orai1 in ECs, the authors used a comprehensive multipronged approach. First, using 3 Orai1 inhibitors with distinct mechanisms of action ...

In fact, Wilkinson hopes an agreement between the Pathways Alliance consortium, Ottawa and Alberta can soon be reached to get one of the world’s largest carbon capture networks moving ...