All but one of the other patients received stem cells from donors with a rare mutation in which part of their CCR5 gene was missing, blocking HIV from entering their body's cells. Those donors had ...

Summary: Maraviroc is the first CCR5 coreceptor antagonist to receive marketing approval from the Food and Drug Administration (FDA) for the treatment of CCR5-tropic human immunodeficiency virus ...

He was targeting a gene called CCR5. This is a set of genetic instructions that are important for a functioning immune system - but they are also the doorway that human immunodeficiency virus (HIV ...

He had targeted a gene called CCR5, which in some people has a variation known to protect against HIV infection. It’s rare for numbers in a spreadsheet to make the hair on your arms stand up ...

The transfer came from a donor that had a rare mutation in part of their DNA called the CCR5 gene. CCR5 is a set of genetic instructions that build the doorway that human immunodeficiency virus ...

艾滋病即获得性免疫缺陷综合征，由人类免疫缺陷病毒（HIV）感染引起。1981年，全球第一例艾滋病患者在美国被发现。随后，无数科学家投身于人类与艾滋病之间的鏖战，殚精竭虑打造出各种“利器”——鸡尾酒疗法、干细胞移植、疫苗预防等，为防治该疾病奠定了坚实基础。

A total of seven individuals worldwide (two patients in Berlin and patients in London, Düsseldorf, New York, City of Hope and Geneva) are considered likely to have been cured or to be in long-term ...

近日，发表在《自然医学》杂志上的一项研究发现，即使艾滋感染者接受的干细胞移植中不携带CCR5△32突变基因，也有可能被治愈。

The stem cells Edmonds received in his transplant had two copies of a rare genetic mutation called CCR5 delta-3, which makes ...

2024年7月22日，第25届国际艾滋病大会(AIDS2024)在德国慕尼黑开幕。

As previously announced, CytoDyn will be partnering with the American Foundation for AIDS Research (amfAR) to sponsor the HIV LATCH study which will use leronlimab to protect CCR5+ donor immune cells ...

These sites bind to coreceptor CCR5 or CXCR4 on the membrane of the host cell (center panel), an event that initiates steps that culminate in the fusion of the HIV envelope with the host cell ...