The FDA informed Intercept that it is unable to approve the sNDA in its current form, consistent with the outcome of the Gastrointestinal Drugs Advisory Committee (GIDAC) meeting in September 2024. In ...

Fetzima (levomilnacipran), Pristiq (desvenlafaxine), and Khedezla (desvenlafaxine) are also common SNRIs and are used to treat major depressive disorder. Savella (milnacipran) is another common SNRI ...

In general, those with variations affecting the genes – namely CYP1A2 and a gene that regulates it, called AHR – tend to break caffeine down more slowly, allowing it to remain in the blood longer. Yet ...