As a promising chimeric antigen receptor (CAR) cell therapy, whether CAR macrophages (CAR-Ms) can be used to treat I/R remains unclear. The expression of FAP (fibroblast activation protein) was ...

The $4.9 billion acquisition of Forty Seven by Gilead is an example of the explosive excitement and investment into macrophage-directed therapies, utilizing CD47 checkpoint blockades ...

近日，良渚实验室 张进团队与中国科学院动物研究所 宋默识研究组合作，在Circulation Research杂志在线发表了题为 “CAR-macrophage therapy alleviates myocardial ...

Researchers advance CAR T cell therapy for solid tumors by innovating ways to overcome the unique barriers of solid tumor ...

Researchers have developed an innovative CAR T-cell therapy to combat glioblastoma, the most common malignant brain tumor in ...

Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this ...

Background Peritoneal metastasis is the most common metastasis pattern of gastric cancer. Patients with gastric cancer ...

See Kailin Yin et al. Second-generation M1-polarized CAR macrophages Induced pluripotent stem (iPS) cell-derived macrophages (iMACs) are being used to engineer CAR macrophages for immunotherapy.