Cardiac hypertrophy, characterized by an increase in heart muscle cell size, is often triggered by various stimuli including pressure overload, which can lead to heart failure if left unchecked.

Congestive heart failure (CHF) is the term used to describe what happens when the heart is unable to pump enough blood to meet the body’s needs. (It should not be confused with cardiac arrest in which ...

has been linked to the advancement of heart failure. A group from Nagoya University Graduate School of Medicine in Japan discovered an enzyme called protein kinase N (PKN) that controls cardiac ...

Bayer's mineralocorticoid receptor antagonist (MRA) Kerendia hit the mark as a treatment for a common form of heart failure in the FINEARTS-HF study, setting up regulatory approvals, but there is ...

To determine the prognostic value of left atrial strain (LAS) using cardiac magnetic resonance for predicting death, heart failure, and ischemic stroke in patients with known or suspected coronary ...

The heart is responsible for pumping oxygen and nutrients throughout the body. In heart failure, the heart is not able to adequately perform its function, either due to problems with filling or ...

Steroidal mineralocorticoid receptor antagonists reduce morbidity and mortality among patients with heart failure and reduced ejection fraction, but their efficacy in those with heart failure and ...

The use of mineralocorticoid receptor antagonists (MRAs) has been well established for patients with heart failure and reduced ejection fraction (HFrEF ... HFrEF is characterised by eccentric cardiac ...

A medication that is currently used for chronic kidney disease in patients with type 2 diabetes has been found to reduce the risk of worsening heart failure and cardiovascular death in certain ...

In terms of the primary composite endpoint of death from cardiovascular causes, aborted cardiac arrest, or hospitalization for heart failure, the rates in TOPCAT were lower among those randomized ...