However, recent studies have indicated new roles for centrosomes in cytokinesis and cell-cycle progression. Is it possible that a common 'thread' connects all three sets of findings? Careful ...

For example, is there an elaborate control machinery, as for DNA, that licenses only one duplication of the centrosome per cell cycle? Sluder and Hinchcliffe state that this is likely in culture ...

Each centrosome pushes the chromosome from each side until they are lined up in the ... Telophase: Have students compare the progression through the cell cycle up to this point. Have them identify ...

Many cancer cells, for example, exhibit abnormal chromosome numbers and extra centrosome. Typically, before such defective ...

Many cancer cells, for example, exhibit abnormal chromosome numbers and extra centrosome. Typically, before such defective cells can survive and grow, they arrest their cell cycle, or trigger ...

The goal of my research is to understand the biogenesis of centrioles/centrosomes and primary cilia, and how defects in these processes affect mammalian cell physiology and evoke stress responses.