Programmed cell death-1, or PD-1, has become a headline-grabbing molecule best known for its role in cancer immunotherapies called checkpoint inhibitors. A study from Georgia Tech and Emory ...
This topic explores the diverse landscape of cell death mechanisms, emphasizing both regulated (non-apoptotic) and apoptotic pathways. We aim to provide an in-depth analysis of how these processes ...
This immune imbalance contributed to evasion of immune destruction and limited the efficacy of programmed cell death protein 1 (PD-1) blockade. Dual checkpoint blockade reprogrammed the immune ...