Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) today reported financial results for the third quarter 2024 and provided a business update. "The Mirum team executed ...
AIM To synthesise fatty acid bile acid conjugates (FABACs) and study their effects on cholesterol crystallisation in bile in vitro and in vivo. METHODS FABACs were prepared by conjugation of cholic ...
The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to ...
However, there is marked heterogeneity in the methodology that makes direct comparison of these studies difficult. Such heterogeneity includes symptom definition (daily-to-monthly reflux symptoms ...
A commissioning policy is a document that defines access to a service for a particular group of patients. A NICE Technology Appraisal Guideline on the same topic will replace, or be incorporated into, ...
Bile acids, such as cholic acid (CA) and chenodeoxycholic acid (CDCA), are modified by gut bacteria into deoxycholic acid (DCA) and lithocholic acid (LCA). These metabolites interact with the ...
The present study suggests the proportions of patients with reflux esophagitis rise up with the increase of GerdQ score, however, a low GerdQ score cannot exclude the possibility of reflux ...
Chemical ecology is the study integrating chemistry and biology to examine the chemical interactions among organisms and their environment. It includes signalling processes and communication ...
Post gallbladder removal surgery, your body might struggle with fat digestion, resulting in problems like discomfort, bloating, and various other digestive issues. A potential remedy for this ...