Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been described as a 'bead on a string'. Chromatin organization strengthens DNA for ...

Human survival is dependent upon an extraordinarily intricate dance that takes place inside every cell and every nucleus. DNA ...

To address this, researchers developed two complementary machine learning models—PRIDICT2.0 and ePRIDICT—to predict prime editing efficiency across various edit types and chromatin contexts.

Why deprotected cohesin is not removed by Wapl remains enigmatic. By reconstituting Wapl-dependent cohesin removal from chromatin in vitro, we discovered a requirement for Nek2a and Cdk1/2-cyclin A2.

By Pooja Toshniwal Paharia The study links genetic and regulatory changes to increased erythrocyte production and leukemia ...

The team generated a large-scale tissue microarray dataset of chromatin images from 560 samples taken from 122 female patients across three disease stages and 11 phenotypic categories. Using advanced ...

The molecular mechanism of high-glucose-induced cognitive impairment in diabetes remains unclear. This work demonstrates that ...

Want your next Windows laptop to feature a number pad? Here's the best you can buy right now. Laptops come in all shapes and sizes these days, which means not every laptop you come across will ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role ...