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Circular RNA: Vaccines, therapeutics and biomarkers could be revolutionised
the mRNA approach may soon be trumped by circular RNA (circRNA). CircRNA is a type of single-stranded RNA that, unlike linear ...
What to Know About MicroRNA, the Nobel-Prizewinning Discovery
This isn't the first time RNA has been honored recently. The molecule has been something of a scientific darling of late: ...
免疫逃逸新机制！中国药科大学合作发文：改善肿瘤治疗效果的新策略
为了探究circPIAS1是否可以通过抑制STAT1磷酸化过程来减轻免疫介导的铁死亡，研究人员对肿瘤组织进行了IHC染色分析。ASO-circPIAS1与PD-1抑制剂的联合治疗导致P-STAT1水平显著升高，而GPX4水平则呈相反趋势。此外，研究人 ...
The Economist1d
A Nobel prize for the discovery of micro-RNA
B efore the committee that awards the Nobel Prize for physiology or medicine made its announcement on October 7th, the ...
Study shows small RNA plays a crucial role in intestinal colonization
The intestinal microbiome is a highly complex ecosystem with thousands of different types of bacteria. Live and let live, ...
They found tiny RNA and how it regulates life’s complexity
Among the many types of RNA are messenger RNA (mRNA), now a familiar name, which carries the information from the DNA to the ...
Nobel Prize in medicine honors 2 scientists for their discovery of microRNA
Two scientists have won the Nobel Prize in physiology or medicine for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that help control what t ...
激活自噬并诱导化疗耐药！郑州大学发文：结直肠癌进展新见解
【导读】环状RNA（circRNA）是一种具有共价闭合单链环状结构的调节性RNA。有证据表明，circRNA在多种癌症的进展和发展中发挥着重要作用。然而，circRNA对结直肠癌（CRC）自噬介导的进展的影响尚不明确。
Nobel Prize in Medicine awarded to Americans for microRNA find
STOCKHOLM − U.S. scientists Victor Ambros and Gary Ruvkun won the 2024 Nobel Prize in Medicine for the discovery of microRNA ...
科学家发现极小型Cas13j蛋白，研发微小型RNA碱基编辑器，拥有100%国内自主知识产权
目的就是希望能够开发 1-2 种具有中国自主知识产权的微小型 RNA 高效基因编辑底层技术，并至少构建一种基于微小型 RNA 编辑工具的遗传性疾病治疗方案。 李果等人和马斌团队沟通之后，后者表示对于新型 CRISPR 系统的挖掘工作也非常感兴趣。于是 ...