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We found that TIPE induced PKM2 dimerization, thereby facilitating its translocation from the cytoplasm to the nucleus. TIPE-mediated PKM2 dimerization consequently promoted HIF-1α activation and ...

HIF(缺氧诱导因子)基因家族成员在氧利用率变化期间作为细胞和全身氧稳态的主要调节者。青藏高原是形成长期缺氧和冷适应天然实验室。在这种情况下，限于3500 m 高海拔淡水河流的硬鳍石斑鱼被选为模型，以与平原的代表性物种大鳞石斑鱼进行比较。我们克隆 ...

Relation between chemical reaction rate and concentrations of the reactants From Wikipedia, the free encyclopedia ...