During DNA replication, the unwinding of strands leaves a single strand vulnerable. How does the cell protect these strands from damage? How would you identify the protein that serves as a ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

Scientists have identified the likely geological and environmental conditions that fostered the development of life as we ...

New research shows that DNA replication in early mouse embryos doesn't follow the expected patterns seen in older cells. A ...

Previous research suggests that about two thirds of the mutations that drive cancer result from errors made during DNA replication. DNA replication is an essential part of cell division. Before a cell ...

DNA is susceptible to damage caused by errors committed during replication and by environmental factors, such as radiation, oxidants, or alkylating agents. Repair reactions involve the excision of ...

A centromere is a specialized location in the DNA that functions as the control center of cell division and is maintained, ...

heat cycling is enough to get them to do the work of DNA replication. The process is called the DNA polymerase chain reaction (PCR). (If it sounds familiar, it's because PCR-powered COVID testing ...

The S phase checkpoint is a kinase signaling cascade that is activated in response to DNA damage or fork stalling during replication stress. Checkpoint activation results in the stabilization of ...

This important work shows how a simple geophysical setting of gas flow over a narrow channel of water can create a physical environment that leads to the isothermal replication of nucleic acids. The ...

Thymine dimers are a common type of UV-induced DNA lesion and are associated with skin cancer risk. During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate ...