Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively obscure, protects bacteria in an entirely different ...

Spontaneous deamination of 5-methyl-cytosines can escape detection by the DNA repair system, which makes methylated CpG dinucleotides mutational hotspots. As a result, over evolutionary time ...

Coconut meat and coconut water have garnered significant attention for their richness in healthful flavonoids. However, the dynamics of flavonoid metabolites in coconut water during different ...

This enables a potent all-in-one editing solution for the development of next-generation cell therapies. Specificity: The ABE demonstrated highly specific on-target deamination with minimum-to-no ...

Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms.

Quantum dots (QDs), also known as nanoparticle-based fluorescent probes, are luminescent semiconductor particles with a size range of 2–20 nm. The unique optical and electronic capabilities of QDs ...

This important paper introduces a theoretical framework and methodology for identifying Cancer Driving Nucleotides (CDNs), primarily based on single nucleotide variant (SNV) frequencies. A variety of ...

Satake and colleagues' important study elucidates somatic mutation processes in plants, demonstrating that in two tropical trees, mutation rates correlate with age, not growth rates. Their convincing ...

Recent advances in next-generation sequencing (NGS) enable researchers to simultaneously capture both genetic and epigenetic information in a single analysis. Traditional sequencing techniques have ...