This reaction, deamination, is about twice as likely to happen when a cytosine is chemically tagged by the addition of a molecule known as a methyl group to create 5-methylcytosine, which occurs ...

If an organism cannot use lactose as a food source it will be forced to use the amino acids / proteins in the media. The deamination of the amino acids creates NH 3, a weak base, which causes the ...

For our purpose here, it is important to mention two kinds of reactions involving amino acid: transamination and deamination. In the first kind of reaction, the enzymes aminotransferases convert ...

A proposed method for DNA demethylation involves sequential oxidation and deamination of 5mC, followed by base excision repair 1. A second epigenetic mechanism implicated in learning and memory ...

In the liver ammonia is formed by the deamination of amino acids. It is highly toxic and cannot be allowed to accumulate in the body. Excess ammonia is converted to urea. Urea and water are ...

Cas9, cuts any RNA or DNA it recognizes as foreign, and thereby protects bacteria from viral attacks. Another CRISPR system, one that is relatively obscure, protects bacteria in an entirely different ...

Inosine is also formed by the deamination of adenosine, a process catalyzed by enzymes called ADARs (adenosine deaminases acting on RNA). Structural formula of inosine. Inosine is a nucleoside ...

Spontaneous deamination of 5-methyl-cytosines can escape detection by the DNA repair system, which makes methylated CpG dinucleotides mutational hotspots. As a result, over evolutionary time ...

Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms.

Mutations can occur when adenine is altered or mismatched with other bases. For example, the deamination of adenine can lead to the formation of hypoxanthine, which can pair with cytosine instead of ...

Specificity: The ABE demonstrated highly specific on-target deamination with minimum-to-no indel formation. Genome-wide analyses confirmed no detectable translocations and no significant genomic ...

In the liver, ammonia is formed by the deamination of amino acids. It is highly toxic and cannot be allowed to accumulate in the body. Excess ammonia is converted to urea. Urea and water are ...