While naldemedine is efficacious for preventing opioid-induced constipation among individuals with cancer, long-term effects should be assessed. Naldemedine significantly prevents opioid-induced ...

Drug-induced lupus is more common in men because they are given these drugs more often; however, not everyone who takes these drugs will develop the disease. Specific criteria for diagnosing ...

In a randomized manufacturer-sponsored study, the peripheral opioid antagonist methylnaltrexone was investigated as therapy for opioid-induced constipation ... four study-drug doses, defecation ...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results From an International Multicenter Study Preventive use of naldemedine for ...

Researchers at University of Tsukuba revealed that administering naldemedine, which is a constipation medication, alongside opioids effectively prevents opioid-induced constipation, thereby ...

Drug-induced valvular heart disease (DIVHD) was first described in the 1960s. Initially, associations with ergot derivatives used for migraine prevention, or with anorectic drugs, were described.

The secondary end points included frequency of spontaneous bowel movements (SBM), quality of life (QOL), and frequency of opioid-induced nausea and vomiting (OINV). Of the 103 patients assessed for ...

Constipation-predominant irritable bowel syndrome (IBS-C) is a condition characterized by chronic constipation with associated abdominal pain. It's a subtype of irritable bowel syndrome (IBS). About ...