thus reducing ECM degradation (Lin et al., 2021). These studies provide valuable insights into the role of autophagy in OA pathogenesis, and offer promising avenues for the development of novel ...

The term osteoarthritis refers to a group of disorders that result in the primarily mechanically induced structural and functional failure of synovial joints. Osteoarthritis is considered a risk ...

1 Department of Rheumatology and Immunology, Affiliated Hospital of Jiangsu University, Zhenjiang, China 2 School of Life Sciences, Jiangsu University, Zhenjiang, China The hypoxic microenvironment, ...

The synovium consists of two layers, lining and sublining. The sublining is composed of Thy1+ fibroblasts, immune cells, blood vessels and nerves in a meshwork of extracellular matrix (ECM). The ...