Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...
In mice, inhibiting protein S-palmitoylation Counteracted accumulation of harmful proteins in neurons and delayed onset and progression of cognitive decline.
An enzyme called EZH2 has an unexpected role in driving aggressive tumor growth in ... of a protein called PKCλ/ι in prostate cancer cells enables EZH2 to drive aggressive growth, even with androgen ...