Despite the notable advancements in cancer pharmacotherapy, such as chemotherapy, targeted therapy, and immunotherapy, which have significantly improved patient survival rates, managing the associated ...

Researchers at University of California San Diego analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance. The findings ...

U.N. experts say there has been a slight drop in the production of opium in Myanmar, the world’s biggest source of the ...

Contrary to previous findings, it is shown that this accelerated resistance development process is dependent on the hindrance of DNA repair, which is completely orthogonal to the SOS response.

New Delhi: Antimicrobial resistance (AMR) remains a significant ... In the South-East Asia region, the risks of AMR are influenced by factors such as population density, limited healthcare access ...

"These factors included income, education, occupation and housing, to identify potential drivers of antimicrobial use," Dr. O'Brien said. Antimicrobials are drugs, chemicals or substances that ...

For example, clones that were no longer responsive to the drug venetoclax (which blocks the survival factor Bcl-2 ... disease progression and therapy resistance, can be identified early and ...

"We can take advantage of this cost to suppress the establishment of antibiotic resistance without drugs or harmful chemicals." Spontaneous mutations of DNA arise in all living cells, including ...

With microbes increasingly evading the effects of the drugs designed to combat them ... challenges when it comes to antibiotic resistance. Factors such as cultural norms, health care systems ...

Their data show how genetic and non-genetic factors determine the functional ... changes contribute to disease progression and drug resistance," says Maija Leppä, first author of the paper.

In this review we consider the effects of orlistat on cardiovascular disease (CVD) risk factors. Furthermore, we present the effects of the combination of orlistat with hypolipidemic drugs ...