The hypoxia-inducible factor HIF promotes the transcription of angiogenesis-related factors.

the principal mechanism by which many cancers develop resistance to chemotherapy drugs, is a major factor in the failure of many forms of chemotherapy. It affects patients with a variety of blood ...

Genomic analysis of malaria parasites reveals which genetic variants are most likely to confer resistance to antimalarial ...

Researchers analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug resistance.

which also contributes to the increase in antimicrobial resistance and MDR in S. pneumoniae. PCV13 may contribute in reducing the spread of drug-resistant 19A pneumococcal clones by its coverage ...

A new method can improve treatment for patients with chronic myeloid leukemia by predicting which medication will be most ...

Soil plays a much bigger role in the spread of antibiotic resistance than one might imagine. Surprisingly, the ground beneath ...

Neonatal mortality remains a global concern, with neonatal sepsis and antimicrobial resistance (AMR) posing significant ...

"What we found was that children with severe malaria do have evidence of drug resistance," says Dr. Chandy John, director of Indiana University School of Medicine's Ryan White Center for ...

It also could also guide the development of new drugs or drug combinations. “We can prevent resistance by developing other drugs that make bedaquiline work better,” Yang said. For example ...

Current treatments, including tyrosine kinase inhibitors (TKIs) that target EGFR, are less effective against non-canonical mutations, leading to poor outcomes and drug resistance. New methods like ...