The CDR1α and CDR3α loops of the iNKT TCR and the galactose headgroup of the α-GalCer analogues generally adopted very similar positions within all the ternary complexes and subtle changes in the ...
(RTTNews) - Biohaven Ltd. (BHVN), Monday announced several clinical and regulatory milestones across its proprietary Molecular Degrader of Extracellular Proteins platform as well as its glutamate ...
Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...
Dec. 13, 2024 — Scientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long ...
The US Food and Drug Administration (FDA) has declined to approve Applied Therapeutics’ govorestat for classic galactosemia, prolonging the wait for the first marketed treatment for the genetic ...
causes a buildup of galactose, leading to an improper conversion to the toxic metabolite galactitol. Accumulation of this molecule causes neurological complications, including deficiencies in ...